Cover Picture: Discovery and Engineering of an Ene‐reductase for Kinetic Resolution and Cascade Reduction of Hajos‐Parrish/Wieland‐Miescher Ketones (Adv. Synth. Catal. 17/2023)

The inside cover picture illustrates that the stepwise reduction of Hajos‐Parrish ketone (HPK) by ene‐reductase (ERED)/ketoreductase (KRED) and KRED/ERED cascade. In this study, the authors discovered an ERED and engineered it as (S)‐stereopreferred enzymes, so that it could be used for kinetic reso...

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Veröffentlicht in:	Advanced synthesis & catalysis 2023-09, Vol.365 (17), p.2764-2764
Hauptverfasser:	Li, Dongyan, Dong, He, Chen, Xianwen, Li, Yangyang, Xu, Yiping, Wang, Jing, Fang, Jiali, Huang, Chenming, Zhang, Wenhe, Jia, Xian, You, Song, Qin, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	cascade reduction ene-reductase Hajos-Parrish/Wieland-Miescher ketones Ketones ketoreductase kinetic resolution Reductases Reduction
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