Effect of Intermittent fasting on weight and glucose control in Type 2 Diabetes Mellitus patients

Background and objectives: Numerous studies suggest that excess body weight is associated with delay the onset of Type 2 Diabetes Mellitus (T2DM). Nowadays, trend of healthy lifestyle is the global trend but the study on the effect of intermittent fasting (IF) in chronic illness like type 2 diabetes are limitation. This study was designed to investigate the relation between the blood sugar levels and the weight control by using intermittent fasting in type 2 Diabetes Meletus (T2DM) patients. Methods: The Method of this study was under the health policy of Chon Buri province. Participants were five patients, who had diagnosis of T2DM and taking Diabetes Mellitus (DM) medicine. Participants were excluded if they had complication of T2DM, kidney disease and history of severe hypoglycemia. The three phase (baseline, intervention and follow up) observational study was designed. Participants reported their meals by photography to the online chat group throughout study stage. The fasting duration were set for participant. The self-monitored blood glucose in morning, afternoon and evening was reported twice week. The online consultation group was created for communicate between participant and the health care professional team. Every month participants were come to hospital for blood checkup and get individually nutrition intervention with dietitian. Results: The five participants on average were overweight (Mean body mass index (BMI) 28.55kg/m2). Average of blood glucose was decrease 36.8 mmol/dL. Three participants can reduce DM medicine. Two of all participants decrease in weight. IF led to overall spontaneous decrease in carbohydrate and caloric intake when compared with baseline as measured by food photography. Two of five participants would continue with modified IF after this study. Conclusions: The result from this pilot study indicated that IF may improve the body weight and fasting glucose levels in T2DM. These finding should be explored for the larger and longer study.