Cationic proteins of neutrophilic granulocytes in the prognosis of purulent-septic postpartum complications in cows

Endometrial epithelial and stromal cells sense molecular patterns associated with pathogens and damage through innate immune receptors, resulting in the release of cytokines and chemokines. These mediators activate and attract neutrophils and macrophages. Cationic proteins of neutrophils are modulators of the body’s inflammatory reactions in sepsis, which is characterized by the presence of microorganisms and their toxins in the blood. The presented studies revealed a significant increase in neutrophilic granulocytes with varying degrees of content of cationic protein granules in them, expressed as a mean cytochemical coefficient. At the same time, there was a lack of marker dynamics in clinical and hematological parameters in case of purulent-septic postpartum complications in cows, which determined the prognostic value of the test for cationic proteins.