99-LB: Myocardial Blood Flow in Association with Baseline Ejection Fraction after Elevation in Plasma Ketones in Patients with T2DM and Heart Failure

99-LB: Myocardial Blood Flow in Association with Baseline Ejection Fraction after Elevation in Plasma Ketones in Patients with T2DM and Heart Failure

Background: SGLT2 inhibitors have been shown to provide CV benefits in HFpEF and HFrEF patients with and without diabetes. The underlying mechanisms continue being explored. Objective: To examine the effect of hyperketonemia on myocardial blood flow (MBF) in patients with HF and T2DM. Methods: Subje...

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2023-06, Vol.72 (Supplement_1), p.1
Hauptverfasser: SOLIS-HERRERA, CAROLINA, QIN, YUEJUAN, HONKA, HENRI, ACOSTA, FRANCISCA M., MOODY, ALEXANDER, CHAVEZ, ALBERTO, TRIPLITT, CURTIS L., CLARKE, GEOFFREY D., CERSOSIMO, EUGENIO, DEFRONZO, RALPH A.
Format: Artikel
Sprache:eng
Schlagworte:
Blood flow
Congestive heart failure
Diabetes
Diabetes mellitus
Ketones
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Zusammenfassung:Background: SGLT2 inhibitors have been shown to provide CV benefits in HFpEF and HFrEF patients with and without diabetes. The underlying mechanisms continue being explored. Objective: To examine the effect of hyperketonemia on myocardial blood flow (MBF) in patients with HF and T2DM. Methods: Subjects with T2DM and HF (EF
ISSN:0012-1797
1939-327X
DOI:10.2337/db23-99-LB