In Situ Reprogrammings of Splenic CD11b+ Cells by Nano‐Hypoxia to Promote Inflamed Damage Site‐Specific Angiogenesis (Adv. Funct. Mater. 32/2023)

Splenic Filtering of Nanoparticles In article number 2302817, Hak‐Joon Sung, Seung Eun Yu, and co‐workers show that the inevitable splenic filtering of nanoparticles can be turned into an advantage. By loading a hypoxia‐mimetic agent onto liposomes, splenic CD11b+ cells undergo vasculogenic reprogra...

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Veröffentlicht in:Advanced functional materials 2023-08, Vol.33 (32), p.n/a
Hauptverfasser: Chung, Seyong, Kim, Si Yeong, Lee, Kyubae, Baek, Sewoom, Ha, Hyun‐Su, Kim, Dae‐Hyun, Park, Suji, Lee, Chan Hee, Kim, Hye‐Seon, Shin, Young Min, Yu, Seung Eun, Sung, Hak‐Joon
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Sprache:eng
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Zusammenfassung:Splenic Filtering of Nanoparticles In article number 2302817, Hak‐Joon Sung, Seung Eun Yu, and co‐workers show that the inevitable splenic filtering of nanoparticles can be turned into an advantage. By loading a hypoxia‐mimetic agent onto liposomes, splenic CD11b+ cells undergo vasculogenic reprogramming, making them home inflamed sites and rescue damaged tissues under ischemia or resection.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.202370196