Tubulointerstitial nephritis and uveitis (TINU) syndrome; an underrecognized entity

Tubulointerstitial nephritis and uveitis syndrome is a rarely seen multi-systemic disease with autoimmune features. Renal and ocular involvement generally occurs asynchronously therefore leads to late diagnosis. Renal manifestations generally precede ocular involvement. Eye disease is almost always of recurrent bilateral anterior uveitis. Renal disease is generally mild, self-limited and rarely requires immunosuppression. Definitive diagnosis is based on histopathological evaluation in the presence of clinical features and exclusion of masquerading disorders. Steroid is the most preferred first line agent, usually suggested for at least 3 to 6 months. Here, our objective with this case report is to attract attention to this uncommon entity in the rheumatology literature.