The Importance of Ischemia Modified Albumin in Chronic Hepatitis B and C

Objectives: In this study, it was aimed to investigate the ischemia modified albumin (IMA) and the IMA/albumin ratio (IMAR) and the relationship between these two parameters with fibrosis in patients with chronic hepatitis B (CHB), hepatitis B e antigen negative chronic infection (HBI) and chronic hepatitis C (CHC). Materials and Methods: This prospective study included 80 patients with CHB, 50 patients with HBI, 30 patients with CHC and 60 control groups. IMA level was measured using rapid colorimetric analysis developed (albumin-cobalt binding test). IMAR was calculated. Results: Forty-two of the CHB cases were female and 38 were male (age range: 46.62±2.69). Thirty of the HBI patients were female and 20 were male (age range: 40.83±3.71). Ten of the cases with CHC were female, and 20 were male (age range: 41.35±3.58). Thirty-three of the control group were female and 27 were male (age range: 30.45±1.08). Serum IMA levels and IMAR, CHB, HBI, and CHC cases were statistically significantly higher than the control group (p