CPPD-related pseudoneuroarthropathy in a patient with myelodysplastic syndrome

The calcium pyrophosphate deposition (CPPD) disease is a common form of crystal arthropathy. It usually affects elderly patients. The clinical and radiological features of CPPD vary widely, so CPPD is a great mimicker of other musculoskeletal conditions. Asymptomatic and destructive forms can present at the same time in the same patients. Several diseases have been proposed to be related to CPPD, but hematologic disorders have not been reported to occur concurrently. Charcot arthropathy (CA) is associated with neuropathy and is characterized by erosive joint disease. Here, we report an interesting CPPD case presenting as pseudo-CA in a patient with myelodysplastic syndrome.