An Interesting Case of Acute Myeloid Leukaemia Presented with Cerebrovascular Embolism and Native Aortic Valve Thrombus Developed Under NOAC Treatment for Pulmonary Embolism

Acute myeloid leukemia (AML) can manifest with different signs and symptoms. Acute pulmonary embolism and cranial vascular events are some of these manifestations. However, development of valvular thrombus in the patients without inheritable thrombophilia is extremely rare. Here, we presented a very rare case of AML manifested with multiple cerebrovascular embolisms and a large, mobile native aortic valve thrombus developed under apixaban treatment for unprovoked pulmonary embolism.