Acid‐catalyzed One Pot Synthesis of Thiazoloindolamines from α‐Diazoimidamides and Thioureas

A novel synthetic method for the formation of thiazolo[4,5‐b]indol‐2‐amines from α‐diazoimidamides and mono‐substituted thioureas in the presence of a catalytic amount of boron trifluoride etherate and camphorsulfonic acid under mild conditions was demonstrated. This methodology has a wide‐ranging scope of α‐diazoimidamides and mono‐substituted thioureas, amenable for upscaling experiments and further transformation.This paper is dedicated with best wishes to Professor Goverdhan Mehta on the occasion of his 80th birthday.