IDDF2023-ABS-0226 Initial results of screening program in mongolia where burdening high gastric cancer

BackgroundMongolia is the leading country in the incidence and mortality rate of gastric cancer. According to the national data, TNM stage at the time of cancer diagnosis, a gastric cancer diagnosis is 0.4% in the carcinoma-in-situ stage, 5.1% in stage I, 15.2% in stage II, 42.7% in stage III and 36.5% in stage IV 36.5% were diagnosed respectively. Whereas almost 80% of people are diagnosed with early-stage of gastric cancer in Japan and Korea, where national cancer screening programs have been initiated for several decades. In 2022 national cancer screening program for upper gastrointestinal neoplasia was initiated; therefore, we aimed to conduct a multi-center study to determine gastric cancer incidence among the Mongolian population.MethodsThe cross-sectional study was performed to examine the detection rate of gastric cancer cases based on a national screening program from May to December 2022. The primary outcomes of this study were to define the detection rate (proportion of positive cases among individuals who underwent endoscopic screening) and to determine the characteristics of the cancer type, including its precursor disease based on histological examination.ResultsDuring the screening program, a total of 34581 participants’ data were collected from 28 endoscopy centers from Ulaanbaatar city and the western eastern, southern, and northern parts of the Mongolian province’s hospitals. The age range of the study participants was 35 to 93 years old. In terms of gender, 56.8% are men and 43.13% are women. The mean with SD age of people diagnosed with gastric cancer was 61.56±1.11, while the mean with SD age of healthy people was 53.84 ± 0.29 (p-value 0.0001). Among them, 113 (0.1%) patients were diagnosed with gastric cancer. The proportion of early-stage gastric cancer cases was 34 (30%) based on endoscopic and histological evaluation. The overall cases included in the national screening program are summarized in Figure 1 (IDDF2023-ABS-0226 Figure 1. Initial result from the national screening program for gastric cancer). ConclusionsThe initiation of the Mongolian national gastric cancer screening program could increase to detect the proportion of gastric cancer in its early stage. Therefore, screening programs should be continuous further. However, the quality of endoscopic examination should be improved. Abstract IDDF2023-ABS-0226 Figure 1Initial result from the national screening program for gastric cancer