How Accurate are Conventional MRI and Sonomammography in Assessment of Suspicious Breast Lesions

Background:Breast cancer is the most invasive malignant tumour in females worldwide and is the second leading cause of cancer death in females after lung cancer. In Egypt, cancer breast is the first common site of tumours among females (32%) and the second common tumour site in both sexes. Aim: The aim of this study is to assess the accuracy of diagnostic performance of quantitative parameters derived from breast ultrasound, conventional mammography as well as T1 and T2 conventional magnetic resonance imaging (MRI) in differentiating suspicious breast masses (BI-RADS III and IV) and to suggest the most accurate imaging combination for early diagnosis and treatment of cancer breast. Results: The study included 30 patients with suspicious breast lesions detected by clinical examination, ultrasound, mammography and conventional MRI. Lesions were analyzed regarding their morphology and pattern. The results of each parameter from the previous modalities were correlated to histo-pathology.In this study sensitivity of sono-mammography was 70% and its specificity was 75%. According to using MRI sensitivity was 100% and specificity was 70% by using morphological and patterns. Conclusion: In comparison with MRI, sonomammography alone lack sensitivity in detection of breast lesions in suspicious cases. MRI with additive modalities is the best imaging modality in detection of malignant cases and exclusion of benign cases.