Oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols, a new approach to the synthesis of benzofuro[3,2-d]pyrimidines

Oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols, a new approach to the synthesis of benzofuro[3,2-d]pyrimidines

A new method for the synthesis of benzofuro[3,2- d ]pyrimidines was developed based on the oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols followed by the intramolecular nucleophilic aromatic substitution reaction.

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Veröffentlicht in:Russian chemical bulletin 2023-04, Vol.72 (4), p.966-971
Hauptverfasser: Shcherbakov, S. V., Aksenov, N. A., Shcherbakova, V. Yu, Magometov, A. Yu, Ivanova, A. Yu, Ovcharov, S. N., Aksenov, A. V.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Articles
Inorganic Chemistry
Organic Chemistry
Oxidation
Phenols
Pyrimidines
Substitution reactions
Synthesis
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Zusammenfassung:A new method for the synthesis of benzofuro[3,2- d ]pyrimidines was developed based on the oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols followed by the intramolecular nucleophilic aromatic substitution reaction.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-023-3861-7