Synthesis, Characterization, Cyclic Voltammetric and Biological Studies of 2-Hydroxy-2-Methyl Propiophenone Sulfaguanidine Azomethine ligand and its Mononuclear Cu(II) Complex

A new Cu (II) complex with Schiff base ligand 2-hydroxy-2-methyl propiophenone sulfaguanidine (HMPSG) has been prepared in alcoholic medium and investigated by elemental analysis and spectroscopic methods. The ligand and its Cu (II) complex were subjected to cyclic voltammetric studies using glassy carbon electrode with variable scan rate at various pH levels. The electrochemical studies show single Irreversible reduction wave for ligand while quasi- reversible wave for its Cu (II) complex. For comparative studies, electrochemical measurements were carried out in different polarity solvents. Various kinetic variables such as charge transfer coefficient (αn), diffusion coefficient (D01/2) rate constant (K0f,h) were also determined from cyclic voltammograms measurement. Further, ligand and its Cu (II) complex were analyzed for antimicrobial studies.