Design, Spectral and Antibacterial Investigations of Some Mixed Ligand Metal Complexes

A novel series of mixed ligand Co(II), Cu(II), and Zn(II) complexes of the type [M(L1)(L2) Cl].2H2O, where HL1= 2-(o-vanillinidenehydrazino)benzimidazole (primary ligand) and L2 = 2,2′-bipyridine (secondary ligand) have been synthesized and investigated by various physico-analytical techniques. The spectral results suggested tridentate nature of the Schiff base and coordinated to the metal ions via azomethine nitrogen, ring nitrogen and deprotonated phenolic oxygen atom. These complexes possess distorted octahedral coordination geometry. Furthermore, antibacterial activities for these compounds against B. subtilis, E. coli and S. typhi have been evaluated. In addition, QSAR and electrostatic potential surface analysis of the Schiff base is carried out.