Catalyst‐free, one‐pot three‐component synthesis of N,3‐diphenybenzoimidazothiazoles and oxybis(1‐phenyl‐2‐(phenylamino)ethanones)

The present work, highlights a highly effective unique procedure for the synthesis of N,3‐diphenybenzo[d]imidazo[2,1‐b]thiazoles and oxybis(1‐phenyl‐2‐(phenylamino)ethanones) via the one‐pot three‐component reaction between aryl glyoxal, aryl amine, and 2‐aminobenzothiazole under catalyst‐free conditions. The present mild and green method uses EtOH without catalyst at reflux conditions. No catalyst with high yields, availability of the starting materials, operational simplicity, cleaner reaction profile, no harmful byproducts, and the isolated products in pure form are the advantages of this protocol. Structures of all the freshly synthesized products have been deduced by their FT‐IR, 1H‐NMR, 13C‐NMR, and elemental analysis.