Effect of anti-resistance exercise intervention on sarcopenia in hemodialysis patients under nanofiber-based composite membrane

To explore the intervention effect of anti-resistance exercise on sarcopenia in hemodialysis patients, the polyvinyl alcohol/polyacrylonitrile nanofiber-based composite membrane (PVA/PAN TFNC) was prepared in this study under optimized conditions, which was compared with traditional polysulfone (PSf) membrane for dialysis performance test. Then, a controlled experiment was used in the hemodialysis treatment of 46 maintenance hemodialysis (MHD) patients with sarcopenia detected in Chengdu First People’s Hospital. The patients from the control group should have 12 weeks of regular exercise, while the intervention group received 12 weeks of anti-resistance exercise intervention. It was found that the optimized PVA/PAN TFNC membrane had good dialysis performance (urea clearance rate of 83.4%, lysozyme clearance rate of 47.6%, and bovine serum albumin (BSA) retention rate of 98.7%). After anti-resistance exercise intervention, there were statistically marked differences in physical activity status (maximum grip strength and daily pace), nutritional status (serum albumin), dialysis adequacy (Kt/V), and quality of life score between the intervention group and the control group ( P