A Previously Undescribed Cleistanthane-Type Diterpenoid from Peniophora incarnate

A newly discovered cleistanthane-type diterpenoid named incarnatin A (1) was isolated from Peniophora incarnate, an endophytic fungus obtained from the roots of Ligusticum chuanxiong. Its absolute configuration was unambiguously elucidated by spectroscopic means including HRMS and NMR combined with...

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Veröffentlicht in:	Records of natural products 2023-05, Vol.17 (3), p.522-528
Hauptverfasser:	Deng, Yun, Li, Meimei, Guo, Wenxiu, Li, Cong-cong, Huo, Xue-yan, Hu, Yunjie, Guo, Dale, Huang, Li-jun, Jiang, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Chinese medicine Porous resins Software
Online-Zugang:	Volltext
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Zusammenfassung:	A newly discovered cleistanthane-type diterpenoid named incarnatin A (1) was isolated from Peniophora incarnate, an endophytic fungus obtained from the roots of Ligusticum chuanxiong. Its absolute configuration was unambiguously elucidated by spectroscopic means including HRMS and NMR combined with ECD calculations. Transcriptome sequencing indicated that 1 could inhibit angiogenesis.
ISSN:	1307-6167 1307-6167
DOI:	10.25135/rnp.374.2210.2619