Updates on HIV and Kidney Disease

Purpose of Review With the advent of antiretroviral therapy, HIV infection has become a chronic disease in developed countries. Recent Findings Non-HIV-driven risk factors for kidney disease, such as APOL1 risk variants and other genetic and environmental factors, have been discovered and are better...

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Veröffentlicht in:	Current HIV/AIDS reports 2023-04, Vol.20 (2), p.100-110
Hauptverfasser:	Cervantes, C. Elena, Atta, Mohamed G.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS-Associated Nephropathy - etiology AIDS-Associated Nephropathy - genetics Anti-Retroviral Agents - adverse effects Antiretroviral therapy Apolipoprotein L1 - genetics Chronic infection Environmental factors HIV HIV Infections - complications HIV Infections - drug therapy Human immunodeficiency virus Humans Kidney diseases Kidney Diseases - complications Medicine Medicine & Public Health Risk Factors Topical Collection on Complications of HIV and Antiretroviral Therapy
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Beschreibung
Zusammenfassung:	Purpose of Review With the advent of antiretroviral therapy, HIV infection has become a chronic disease in developed countries. Recent Findings Non-HIV-driven risk factors for kidney disease, such as APOL1 risk variants and other genetic and environmental factors, have been discovered and are better described. Consequently, the field of HIV-associated kidney disease has evolved with greater attention given to traditional risk factors of CKD and antiretroviral treatment’s nephrotoxicity. Summary In this review, we explore risk factors of HIV-associated kidney disease, diagnostic tools, kidney pathology in HIV-positive individuals, and antiretroviral therapy-associated nephrotoxicity.
ISSN:	1548-3568 1548-3576
DOI:	10.1007/s11904-023-00645-1