T1 mapping and reduced field‐of‐view DWI at 3.0T MRI for differentiation of thyroid papillary carcinoma from nodular goiter

BackgroundReduced field‐of‐view diffusion‐weighted imaging (rFOV‐DWI) could be proved to quantitatively identify papillary thyroid carcinoma (PTC) and there is no literature regarding the use of T1 mapping to distinguish nodular goiter (NG) from PTC.PurposeTo compare T1 mapping with rFOV‐DWI in differentiating NG and PTC.Study TypeProspective study.PopulationsNinety‐five hospitalized patients with thyroid nodules were included in the research.SequenceAll subjects underwent T1‐weighted imaging, T2‐weighted imaging, rFOV‐DWI and T1‐mapping sequences.AssessmentThe apparent diffusion coefficient (ADC) and T1 values of each thyroid nodule were measured, respectively. According to pathological results, the thyroid nodules were divided into two groups: Group 1 (NG) and Group 2 (PTC).Statistical TestsAn independent sample t test was used to evaluate the differences of ADC and T1 between the two groups. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic efficiency of T1, ADC, Thyroid Imaging Reporting and Data System (TI‐RADS) and T1 and ADC.ResultsThe T1 and ADC values of nodular goiter were both higher than those of PTC (p