The Pandemic Puzzle—Reviewing the Existing Pieces, Searching for the Missing Ones

The research carried out on socioeconomic implication models of (re)emerging infectious diseases triggering pandemics has shown us that these largely depended on infection transmission, conditioned by the type of pathogen and the human host. Also, these depended on certain external factors, such as the phenomenon of globalization, pollution, fragile health systems, modification of human behaviors, expansion of human habitat near the outbreaks, favorable vectors involved in the transmission and development of new pandemics and last but not least of wars or civil revolts. The present research attempts to provide some responses to the following questions: 1. What have been the most recent and important emerging infectious disease pandemics and what were the risk factors? 2. What was the socioeconomic impact generated by these pandemics and what important lessons did we learn/identify? 3. What measures and/or directions must be implemented/addressed to prevent/possibly stop a future wave of infections or a new pandemic? The answers to these questions are substantiated by different indicators (transmission potential and pathogen severity) through which we focused to offer some suggestions/directions regarding the way in which these pandemics could be anticipated or prevent, indicators that otherwise are already used by public authorities in the development and exploration of intervention strategies. However, through the elaboration and staged presentation of how these pandemics acted as well as the socioeconomic implications and human reactions, this research could be useful in leading to the development of new, effective ways to prevent the transmission of (re)emerging infectious diseases.