A highly sensitive electrochemical biosensor via short-stranded DNA activating LAMP(H+) to regulate i-motif folds for signal transduction

Exploring loop-mediated isothermal amplification (LAMP)-based electrochemical assay for short-stranded DNA biomarkers is intriguing. Herein, a HIV-specific DNA segment (tDNA) was introduced to implement a variant LAMP reaction, where the generated by-products H+, vLAMP(H+), acted as signal transduce...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2023-04, Vol.380, p.133354, Article 133354
Hauptverfasser:	Gao, Jiaxi, Yang, Chunli, Wu, Xu, Huang, Weixiang, Ye, Jingjing, Yuan, Ruo, Xu, Wenju
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biosensors Electrochemical biosensor Electrodes Elongated structure I-motif folds Short-stranded DNA biomarker Signal transduction Transducers Variant loop-mediated isothermal amplification vLAMP(H+) signal transducer
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