Immunologie profile of patients suffering from herpes simplex virus (HSV) -associated oral lesions treated with natural human interferon alpha (Egiferon)

Immunologie profile of patients suffering from herpes simplex virus (HSV) -associated oral lesions treated with natural human interferon alpha (Egiferon)

10 consecutive patients with HSV-associated chronic oral lesions were treated with Egiferon for ten days. There were a statistically significant increase in the Large Granule Lymphocyte (LGL) counts and the number of spontaneous E rosette forming cells by the end of the treatment period. Interferon...

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Veröffentlicht in:Pathology oncology research 1997-03, Vol.3 (1), p.44-46
Hauptverfasser: KÖvesi, György, PÁlÓczi, Katalin, Ónody, Klára, Fekete, Béla
Format: Artikel
Sprache:eng
Schlagworte:
CD14 antigen
CD20 antigen
CD25 antigen
CD3 antigen
CD4 antigen
CD8 antigen
Cell surface
Herpes simplex
Herpes viruses
Interferon
Lymphocytes
Medical research
Oncology
Pathology
Statistical analysis
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Zusammenfassung:10 consecutive patients with HSV-associated chronic oral lesions were treated with Egiferon for ten days. There were a statistically significant increase in the Large Granule Lymphocyte (LGL) counts and the number of spontaneous E rosette forming cells by the end of the treatment period. Interferon alpha brought about a preferential expression of CD8, CDllb, CD14, CD25 and CD45RO cell surface molecules without any effect on the expression of CD2, CD3, CD4, CD20 and HLA-DR.[PUBLICATION ABSTRACT]
ISSN:1219-4956
1532-2807
DOI:10.1007/BF02893352