Pregabalin intoxication-induced Prolonged PR Interval on Electrocardiogram

Pregabalin is a lipophilic analogue of gamma-aminobutyric acid (GABA) and has a similar chemical structure to gabapentin and is more potent than gabapentin. This report documents the case of a 28-year-old male presenting with suicidal attempt by pregabalin intake. The patient had an abnormal PR inte...

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Veröffentlicht in:Journal of clinical and experimental investigations 2018-06, Vol.9 (2), p.100
Hauptverfasser: Şengüldür, Erdinç, Katı, Celal, Aksoy, İskender, Yardan, Türker, Baydin, Ahmet
Format: Artikel
Sprache:eng
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Zusammenfassung:Pregabalin is a lipophilic analogue of gamma-aminobutyric acid (GABA) and has a similar chemical structure to gabapentin and is more potent than gabapentin. This report documents the case of a 28-year-old male presenting with suicidal attempt by pregabalin intake. The patient had an abnormal PR interval (reversible AV-block). He was managed with general supportive care and symptomatic approach such as discontinuation of the drug, hydration with IV fluids, oxygenation, gastric lavage and activated charcoal administration.
ISSN:1309-6621
1309-6621
DOI:10.5799/jcei.433821