Synthesis of New Isoquinoline Derivatives from the Condensation Products of Acid Anhydrides and 2-(3,4-Dimethoxyphenyl)ethanamine

Synthesis of New Isoquinoline Derivatives from the Condensation Products of Acid Anhydrides and 2-(3,4-Dimethoxyphenyl)ethanamine

A simple and convenient method has been proposed for the synthesis of new isoquinoline derivatives via intramolecular cyclization of imides obtained from acid anhydrides and 2-(3,4-dimethoxyphenyl)ethanamine (homoveratrylamine). The cyclization was carried out by treatment with sodium tetrahydridobo...

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Veröffentlicht in:Russian journal of organic chemistry 2022-12, Vol.58 (12), p.1984-1988
Hauptverfasser: Sakhautdinov, I. M., Malikova, R. N., Sakhautdinova, G. F., Abdullin, M. F., Nugumanov, T. R., Mustafin, A. G.
Format: Artikel
Sprache:eng
Schlagworte:
Acidic oxides
Chemistry
Chemistry and Materials Science
Condensates
Hydrogen chloride
Imides
Organic Chemistry
Synthesis
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Beschreibung
Zusammenfassung:A simple and convenient method has been proposed for the synthesis of new isoquinoline derivatives via intramolecular cyclization of imides obtained from acid anhydrides and 2-(3,4-dimethoxyphenyl)ethanamine (homoveratrylamine). The cyclization was carried out by treatment with sodium tetrahydridoborate and aqueous hydrogen chloride.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428022120302