The calcination temperature effect in the synthesis of nanohydroxyapatite: characterization and its application as a nanocarrier
Drug delivery is the process of administering drugs at a specific amount in a specific site. Hydroxyapatite (HA) is reported as a drug carrier because of its unique properties such as high biodegradability, biocompatibility and drug-loading capacity, easy preparation, sterilization and cost-effectiv...
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| Veröffentlicht in: | Applied nanoscience 2023, Vol.13 (1), p.213-219 |
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| creator | Mohammadi, F. Hosseini, Sh Khaksar, S. Chekin, F. |
| description | Drug delivery is the process of administering drugs at a specific amount in a specific site. Hydroxyapatite (HA) is reported as a drug carrier because of its unique properties such as high biodegradability, biocompatibility and drug-loading capacity, easy preparation, sterilization and cost-effective production. In the present study, the nanohydroxyapatite was synthesized at various calcination temperatures by the sol–gel route. The results revealed that the synthesized HA at 700 °C had the highest crystallinity. Moreover, the loading content of ampicillin was studied on HA samples synthesized at different calcination temperatures. It is considered that synthesized HA at 500 °C provided appropriate surface for ampicillin loading. The synthesized HA was characterized by scanning electron microscopy, X-ray diffraction, Fourier transform infrared and UV/Vis spectroscopy techniques before and after ampicillin loading. |
| doi_str_mv | 10.1007/s13204-020-01603-8 |
| format | Article |
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Hydroxyapatite (HA) is reported as a drug carrier because of its unique properties such as high biodegradability, biocompatibility and drug-loading capacity, easy preparation, sterilization and cost-effective production. In the present study, the nanohydroxyapatite was synthesized at various calcination temperatures by the sol–gel route. The results revealed that the synthesized HA at 700 °C had the highest crystallinity. Moreover, the loading content of ampicillin was studied on HA samples synthesized at different calcination temperatures. It is considered that synthesized HA at 500 °C provided appropriate surface for ampicillin loading. The synthesized HA was characterized by scanning electron microscopy, X-ray diffraction, Fourier transform infrared and UV/Vis spectroscopy techniques before and after ampicillin loading.</description><subject>Ampicillin</subject><subject>Antibiotics</subject><subject>Biocompatibility</subject><subject>Biodegradability</subject><subject>Chemistry and Materials Science</subject><subject>Drug carriers</subject><subject>Fourier transforms</subject><subject>Hydroxyapatite</subject><subject>Materials Science</subject><subject>Membrane Biology</subject><subject>Nanochemistry</subject><subject>Nanoscience & Nanotechnology</subject><subject>Nanotechnology</subject><subject>Nanotechnology and Microengineering</subject><subject>Original Article</subject><subject>Roasting</subject><subject>Science & Technology</subject><subject>Science & Technology - Other Topics</subject><subject>Sol-gel processes</subject><subject>Sterilization</subject><subject>Synthesis</subject><subject>Temperature effects</subject><issn>2190-5509</issn><issn>2190-5517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><recordid>eNqNkE1PGzEQhlcIJBDlD3CyxLFaOv7cdW9V1NJKkbjQs-V4Z4mjYC-2ozY99afjZBG9Vfgy9uh9xvbTNNcUbilA9ylTzkC0wKAFqoC3_UlzwaiGVkranb7tQZ83VzlvoC4pOsXlRfP3YY3E2a3zwRYfAyn4NGGyZZeQ4DiiK8TXbk3lfagl-0ziSIINcb0fUvy9t1MlC34mbm2TdQWT_zPPsmEgvmRip2nr3WuvHo-0syl5TB-as9FuM1691svm57evD4vv7fL-7sfiy7J1XPHSosIBRceVEFoM0AuQmnOUICSMsmfYI0ipVhoHy0fFQGkqoaKKIx9kxy-bm3nulOLzDnMxm7hLoV5pWNdR6ECzQ4rNKZdizglHMyX_ZNPeUDAH2WaWbapsc5Rt-gp9nKFfuIpjdh6DwzfwIFsDU6AP3kVN9-9PL3w5alvEXSgV5TOaazw8Yvr3h_887wVVbKOd</recordid><startdate>2023</startdate><enddate>2023</enddate><creator>Mohammadi, F.</creator><creator>Hosseini, Sh</creator><creator>Khaksar, S.</creator><creator>Chekin, F.</creator><general>Springer International Publishing</general><general>Springer Nature</general><general>Springer Nature B.V</general><scope>AOWDO</scope><scope>BLEPL</scope><scope>DTL</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-6683-7407</orcidid><orcidid>https://orcid.org/0000-0003-0563-0370</orcidid></search><sort><creationdate>2023</creationdate><title>The calcination temperature effect in the synthesis of nanohydroxyapatite: characterization and its application as a nanocarrier</title><author>Mohammadi, F. ; Hosseini, Sh ; Khaksar, S. ; Chekin, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c363t-e6ede47364494d08405933e50450f582e8e0556b9eda3f6206915036363e3d573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Ampicillin</topic><topic>Antibiotics</topic><topic>Biocompatibility</topic><topic>Biodegradability</topic><topic>Chemistry and Materials Science</topic><topic>Drug carriers</topic><topic>Fourier transforms</topic><topic>Hydroxyapatite</topic><topic>Materials Science</topic><topic>Membrane Biology</topic><topic>Nanochemistry</topic><topic>Nanoscience & Nanotechnology</topic><topic>Nanotechnology</topic><topic>Nanotechnology and Microengineering</topic><topic>Original Article</topic><topic>Roasting</topic><topic>Science & Technology</topic><topic>Science & Technology - Other Topics</topic><topic>Sol-gel processes</topic><topic>Sterilization</topic><topic>Synthesis</topic><topic>Temperature effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mohammadi, F.</creatorcontrib><creatorcontrib>Hosseini, Sh</creatorcontrib><creatorcontrib>Khaksar, S.</creatorcontrib><creatorcontrib>Chekin, F.</creatorcontrib><collection>Web of Science - Science Citation Index Expanded - 2020</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>CrossRef</collection><jtitle>Applied nanoscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohammadi, F.</au><au>Hosseini, Sh</au><au>Khaksar, S.</au><au>Chekin, F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The calcination temperature effect in the synthesis of nanohydroxyapatite: characterization and its application as a nanocarrier</atitle><jtitle>Applied nanoscience</jtitle><stitle>Appl Nanosci</stitle><stitle>APPL NANOSCI</stitle><date>2023</date><risdate>2023</risdate><volume>13</volume><issue>1</issue><spage>213</spage><epage>219</epage><pages>213-219</pages><issn>2190-5509</issn><eissn>2190-5517</eissn><abstract>Drug delivery is the process of administering drugs at a specific amount in a specific site. Hydroxyapatite (HA) is reported as a drug carrier because of its unique properties such as high biodegradability, biocompatibility and drug-loading capacity, easy preparation, sterilization and cost-effective production. In the present study, the nanohydroxyapatite was synthesized at various calcination temperatures by the sol–gel route. The results revealed that the synthesized HA at 700 °C had the highest crystallinity. Moreover, the loading content of ampicillin was studied on HA samples synthesized at different calcination temperatures. It is considered that synthesized HA at 500 °C provided appropriate surface for ampicillin loading. 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| subjects | Ampicillin Antibiotics Biocompatibility Biodegradability Chemistry and Materials Science Drug carriers Fourier transforms Hydroxyapatite Materials Science Membrane Biology Nanochemistry Nanoscience & Nanotechnology Nanotechnology Nanotechnology and Microengineering Original Article Roasting Science & Technology Science & Technology - Other Topics Sol-gel processes Sterilization Synthesis Temperature effects |
| title | The calcination temperature effect in the synthesis of nanohydroxyapatite: characterization and its application as a nanocarrier |
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