Usefulness of the predicted percentage ventilatory efficiency for carbon dioxide output during exercise in patients with chronic heart failure
The ventilatory efficiency for carbon dioxide output ( V ˙ CO 2 ) during exercise, as measured by the minute ventilation vs. V ˙ CO 2 slope ( V ˙ E vs. V ˙ CO 2 slope), is a powerful prognostic index in patients with chronic heart failure (CHF). This measurement is higher in women than in men, and i...
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| Veröffentlicht in: | Heart and vessels 2023, Vol.38 (1), p.56-65 |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The ventilatory efficiency for carbon dioxide output (
V
˙
CO
2
) during exercise, as measured by the minute ventilation vs.
V
˙
CO
2
slope (
V
˙
E vs.
V
˙
CO
2
slope), is a powerful prognostic index in patients with chronic heart failure (CHF). This measurement is higher in women than in men, and it increases with age. This study aimed to investigate the usefulness of the predicted value of the percentage
V
˙
E vs.
V
˙
CO
2
slope (%
V
˙
E vs.
V
˙
CO
2
slope) as a prognostic index in patients with CHF. A total of 320 patients with CHF and a left ventricular ejection fraction (LVEF) 120 and 15.0% (95% CI 9.4–21.8%) in patients with %
V
˙
E vs.
V
˙
CO
2
slope ≤ 120. The multivariate Cox regression analysis indicated that a %
V
˙
E vs.
V
˙
CO
2
slope > 120 was an independent predictor of cardiovascular-related death (adjusted hazard ratio, 3.24; 95% confidence interval 1.65–6.67;
p
|
|---|---|
| ISSN: | 0910-8327 1615-2573 |
| DOI: | 10.1007/s00380-022-02132-w |