Multifunctional 4D‐Printed Sperm‐Hybrid Microcarriers for Assisted Reproduction (Adv. Mater. 50/2022)

Multifunctional 4D‐Printed Sperm‐Hybrid Microcarriers for Assisted Reproduction (Adv. Mater. 50/2022)

Robotic Microcarriers In article number 2204257, Oliver G. Schmidt, Mariana Medina‐Sánchez, and co‐workers report the development of 4D‐printed multifunctional sperm‐hybrid microcarriers containing soft and smart materials made with two‐photon lithography. These multifunctional facets enable in situ...

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Veröffentlicht in:Advanced materials (Weinheim) 2022-12, Vol.34 (50), p.n/a
Hauptverfasser: Rajabasadi, Fatemeh, Moreno, Silvia, Fichna, Kristin, Aziz, Azaam, Appelhans, Dietmar, Schmidt, Oliver G., Medina‐Sánchez, Mariana
Format: Artikel
Sprache:eng
Schlagworte:
4D‐printing lithography
assisted fertilization
biohybrid micromotors
enzyme‐loaded polymersomes
Gametocytes
Materials science
multifunctional sperm‐hybrid microcarriers
Smart materials
targeted cargo‐delivery
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Zusammenfassung:Robotic Microcarriers In article number 2204257, Oliver G. Schmidt, Mariana Medina‐Sánchez, and co‐workers report the development of 4D‐printed multifunctional sperm‐hybrid microcarriers containing soft and smart materials made with two‐photon lithography. These multifunctional facets enable in situ sperm capacitation/hyperactivation, and the local degradation of the cumulus complex that surrounds the oocyte, both to facilitate the sperm–oocyte interaction for the ultimate goal of in vivo assisted fertilization.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202270346