Self-Destructive Behavior among Predictors of Cancer Incidence

Human cancer is typical for the elderly. Therefore, the genetic predisposition to it is not the subject of negative intraspecific selection. This creates a risk of accumulation of a gene pool of disorders (mutations, unstable genomes), for which an increased risk of malignant neoplasms is only one o...

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Veröffentlicht in:Biology bulletin reviews 2022, Vol.12 (6), p.638-648
Hauptverfasser: Schäfer, T. V., Vakunenkova, O. A., Firsov, K. V., Ivnitsky, Ju. Ju
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Sprache:eng
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Zusammenfassung:Human cancer is typical for the elderly. Therefore, the genetic predisposition to it is not the subject of negative intraspecific selection. This creates a risk of accumulation of a gene pool of disorders (mutations, unstable genomes), for which an increased risk of malignant neoplasms is only one of the phenotypic manifestations in the population. This danger is counteracted by non-tumor pathology, which reduces the likelihood of an individual participating in reproduction. Inherited together with an increased predisposition to malignant neoplasms, it naturally precedes them and often manifests in behavioral disorders. A self-destructive behavior is one form of behavioral disorder. The article considers the hypothesis of smoking and overeating as patterns of species-specific self-destructive behavior, the predisposition to which is inherited together with an increased risk of malignant neoplasms. Approaches to testing the hypothesis by applying a system of incentives that block self-destructive behavior are proposed.
ISSN:2079-0864
2079-0872
DOI:10.1134/S2079086422060081