Colloids Based on Calixresorcins for the Adsorption, Conversion, and Delivery of Bioactive Substances

This review presents the materials on the creation of colloid systems based on calixresorcins derivatives and their application in the targeted delivery of bioactive substances and enzyme-like catalysis. Calixresorcins represent macrocyclic oligomers, which are products from the condensation of resorcins and aldehydes. A cup-like shape of molecules preorganize their functional groups in two directions to influence their self-assembly and recognition of substrates. In the review, some strategies for the formation of calixresorcins ensembles in organic and aqueous media are considered, and the dependence of their morphology on the conformation of calixresorcins and the structure of tail groups is discussed. Some examples of polymer colloids synthesized by the intermolecular covalent crosslinking of calixresorcins derivatives are given. The application of the mentioned colloids in the bonding of bioactive substances for their chemical conversion and targeted transport is shown.