Management of Treatment Resistant Schizophrenia Unresponsive to Clozapine

A recent challenge in schizophrenia has been the management of patients who have failed to respond not only to standard therapeutic regimes but also to trials of atypical neuroleptics such as clozapine and risperidone. This article focuses on the further psychological and pharmacological management...

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Veröffentlicht in:	British journal of psychiatry 1996-12, Vol.169 (S31), p.31-40
Hauptverfasser:	Barnes, Thomas R. E., McEvedy, Christopher J. B., Nelson, Hazel E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antipsychotic Agents - administration & dosage Antipsychotic Agents - adverse effects Clozapine - administration & dosage Clozapine - adverse effects Combined Modality Therapy Dose-Response Relationship, Drug Drug Administration Schedule Drug Therapy, Combination Humans Patient Compliance - psychology Psychotropic Drugs - administration & dosage Psychotropic Drugs - adverse effects Schizophrenia - classification Schizophrenia - diagnosis Schizophrenia - drug therapy Schizophrenic Psychology
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Beschreibung
Zusammenfassung:	A recent challenge in schizophrenia has been the management of patients who have failed to respond not only to standard therapeutic regimes but also to trials of atypical neuroleptics such as clozapine and risperidone. This article focuses on the further psychological and pharmacological management of such patients.
ISSN:	0007-1250 0960-5371 1472-1465
DOI:	10.1192/S0007125000298590