Coronavirus peplomer interaction
By virtue of their lack of motility, viruses rely entirely on their own temperature (Brownian motion) to position themselves properly for cell attachment. Spiked viruses use one or more spikes (called peplomers) to attach. The coronavirus uses adjacent peplomer pairs. These peplomers, identically ch...
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Veröffentlicht in: | Physics of fluids (1994) 2022-11, Vol.34 (11), p.113109-113109 |
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Sprache: | eng |
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Zusammenfassung: | By virtue of their lack of motility, viruses rely entirely on their own temperature
(Brownian motion) to position themselves properly for cell attachment. Spiked viruses use
one or more spikes (called peplomers) to attach. The coronavirus uses adjacent peplomer
pairs. These peplomers, identically charged, repel one another over the surface of their
convex capsids to form beautiful polyhedra. We identify the edges of these polyhedra with
the most important peplomer hydrodynamic interactions. These convex capsids may or may not
be spherical, and their peplomer population declines with infection time. These peplomers
are short, equidimensional, and bulbous with triangular bulbs. In this short paper, we
explore the interactions between nearby peplomer bulbs. By interactions, we mean the
hydrodynamic interferences between the velocity profiles caused by the drag of the
suspending fluid when the virus rotates. We find that these peplomer hydrodynamic
interactions raise rotational diffusivity of the virus, and thus affect its ability to
infect. |
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ISSN: | 1070-6631 1089-7666 |
DOI: | 10.1063/5.0120167 |