Comparative study of brainstem auditory evoked responses in females having premenstrual symptoms with normal population

Materials and Methods: BAEP was conducted on 60 females age group of 18-40 years in two groups in Research laboratory, Department of Physiology, Lala Lajpat Rai Memorial Medical College in collaboration with SVBP Hospital, Meerut for 6 months. Conclusion: Premenstrual symptoms females are showing few significant changes in auditory responses at mid brain level as recorded by BAEP study which can be due to the modulatory effect of female gonadal hormones progesterone and estrogen on neurotransmitters (serotonin, gamma-aminobutyric acid, and glutamate) in central nervous system. [10] The ovarian hormones directly affect cochlea and auditory pathways which could indirectly influence the central processing through other pathways modulating the blood flow in the cochlea and the brain. [12] Changing hormonal levels during menstrual cycle lead to both physical and emotional changes in a woman's body frequently being observed, which somewhat leads to change in conduction velocity in the central auditory pathways.