Assessment of soluble receptor for advance glycation end product level in patients suffering from sickle cell anemia related with nephropathy
Inherited hemolytic anemia represented by sickle cell disesae characterized by subsituition of valine for glutamic and causing adjusment of hemoglobin (Hb) quality also it was realized that Hb molecule subsituation of the β-globin chain at six circumstance caused to transfer of normal adult hemoglob...
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| creator | Kadhim, Doaa Amer Al-Dujaili, Arshad Noori |
| description | Inherited hemolytic anemia represented by sickle cell disesae characterized by subsituition of valine for glutamic and causing adjusment of hemoglobin (Hb) quality also it was realized that Hb molecule subsituation of the β-globin chain at six circumstance caused to transfer of normal adult hemoglobin (HbA), to sickle hemoglobin (HbS). Current study was design to evaluate avery important markers for prediction or as prognostic to sickle cell anemia disease represented by Receptor for Advance of Glycation End Product (RAGE). Methods: The study was carried out in Al–Najaf province in Al-Zahraa TeachingHospital espically by cross-sectional study investigation at duration time from first July to tirty of November, 2019. This investigation was included fifty-five (suffering from sickle cell disease at age from 3-49 years, also appearantly healthy group as number was thirty. Evaluation of all critria were done by using Elisa technique for (RAGE) level and creatinine concentration and made a relatiom between both RAGE and creatinine with some of critria such as gender, body mass index, duration of disease and age .Results: Decrement was indicated significantly (P-Value |
| doi_str_mv | 10.1063/5.0093623 |
| format | Conference Proceeding |
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Current study was design to evaluate avery important markers for prediction or as prognostic to sickle cell anemia disease represented by Receptor for Advance of Glycation End Product (RAGE). Methods: The study was carried out in Al–Najaf province in Al-Zahraa TeachingHospital espically by cross-sectional study investigation at duration time from first July to tirty of November, 2019. This investigation was included fifty-five (suffering from sickle cell disease at age from 3-49 years, also appearantly healthy group as number was thirty. Evaluation of all critria were done by using Elisa technique for (RAGE) level and creatinine concentration and made a relatiom between both RAGE and creatinine with some of critria such as gender, body mass index, duration of disease and age .Results: Decrement was indicated significantly (P-Value<0.05) in Creatinine concentration, also increment (P-Value<0.05) Receptor for Advance of Glycation End Product (RAGE) level of in sickle cell anemia patients than control group. Serum Receptor for Advance of Glycation End Product (RAGE) indicated more significant levels for sickle cell anemia patients than healthy controls. Conclusion: The current study consider as aprediction of patients suffering from sickle cell disease and relation of RAGE with early renal disorder also with some complication.</description><identifier>ISSN: 0094-243X</identifier><identifier>EISSN: 1551-7616</identifier><identifier>DOI: 10.1063/5.0093623</identifier><identifier>CODEN: APCPCS</identifier><language>eng</language><publisher>Melville: American Institute of Physics</publisher><subject>Anemia ; Body size ; Creatinine ; Evaluation ; Hemoglobin ; Receptors ; Sickle cell anemia ; Sickle cell disease ; Valine</subject><ispartof>AIP conference proceedings, 2022, Vol.2398 (1)</ispartof><rights>Author(s)</rights><rights>2022 Author(s). Published by AIP Publishing.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://pubs.aip.org/acp/article-lookup/doi/10.1063/5.0093623$$EHTML$$P50$$Gscitation$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,794,4512,23930,23931,25140,27924,27925,76384</link.rule.ids></links><search><contributor>Ali, Tammar Hussein</contributor><contributor>Kadhem, Safaa Kareem</contributor><contributor>Al-Mussawi, Hana Kadum</contributor><contributor>Almurshedi, Ahmed Fadhil</contributor><contributor>Majeed, Sadiq</contributor><contributor>Hussain, Firas Faeq K.</contributor><contributor>Jawad, Laith Abdul Hassan M.</contributor><creatorcontrib>Kadhim, Doaa Amer</creatorcontrib><creatorcontrib>Al-Dujaili, Arshad Noori</creatorcontrib><title>Assessment of soluble receptor for advance glycation end product level in patients suffering from sickle cell anemia related with nephropathy</title><title>AIP conference proceedings</title><description>Inherited hemolytic anemia represented by sickle cell disesae characterized by subsituition of valine for glutamic and causing adjusment of hemoglobin (Hb) quality also it was realized that Hb molecule subsituation of the β-globin chain at six circumstance caused to transfer of normal adult hemoglobin (HbA), to sickle hemoglobin (HbS). Current study was design to evaluate avery important markers for prediction or as prognostic to sickle cell anemia disease represented by Receptor for Advance of Glycation End Product (RAGE). Methods: The study was carried out in Al–Najaf province in Al-Zahraa TeachingHospital espically by cross-sectional study investigation at duration time from first July to tirty of November, 2019. This investigation was included fifty-five (suffering from sickle cell disease at age from 3-49 years, also appearantly healthy group as number was thirty. Evaluation of all critria were done by using Elisa technique for (RAGE) level and creatinine concentration and made a relatiom between both RAGE and creatinine with some of critria such as gender, body mass index, duration of disease and age .Results: Decrement was indicated significantly (P-Value<0.05) in Creatinine concentration, also increment (P-Value<0.05) Receptor for Advance of Glycation End Product (RAGE) level of in sickle cell anemia patients than control group. Serum Receptor for Advance of Glycation End Product (RAGE) indicated more significant levels for sickle cell anemia patients than healthy controls. Conclusion: The current study consider as aprediction of patients suffering from sickle cell disease and relation of RAGE with early renal disorder also with some complication.</description><subject>Anemia</subject><subject>Body size</subject><subject>Creatinine</subject><subject>Evaluation</subject><subject>Hemoglobin</subject><subject>Receptors</subject><subject>Sickle cell anemia</subject><subject>Sickle cell disease</subject><subject>Valine</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2022</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNp9kU1LAzEQhoMoWKsH_0HAm7A1H002OZbiFxS8KHhb0s1suzVN1mS30h_hfzZqwZuHYWDmnWd4ZxC6pGRCieQ3YkKI5pLxIzSiQtCilFQeo1GuTgs25a-n6CylDSFMl6Uaoc9ZSpDSFnyPQ4NTcMPSAY5QQ9eHiJscxu6MrwGv3L42fRs8Bm9xF4Md6h472IHDrcdd7mVMwmloGoitX-Emhi1Obf2WkTU4h42HbWsy3pkeLP5o-zX20K1jyNPr_Tk6aYxLcHHIY_Ryd_s8fygWT_eP89mi6BjhvDAARAltuV5SzRi12kguJdOCgWVSq6WeClLKkppaQakaKkutmRSWUaIk5WN09cvNJt4HSH21CUP0eWXFSqaYUoSLrLr-VaW67X-MV11stybuq12IlagOp6462_wnpqT6_s3fAP8CbaGCAQ</recordid><startdate>20221025</startdate><enddate>20221025</enddate><creator>Kadhim, Doaa Amer</creator><creator>Al-Dujaili, Arshad Noori</creator><general>American Institute of Physics</general><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20221025</creationdate><title>Assessment of soluble receptor for advance glycation end product level in patients suffering from sickle cell anemia related with nephropathy</title><author>Kadhim, Doaa Amer ; Al-Dujaili, Arshad Noori</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2033-aee0859d39b19221d9a63662952ed2698b94507671ac8e78f16799265d2108613</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anemia</topic><topic>Body size</topic><topic>Creatinine</topic><topic>Evaluation</topic><topic>Hemoglobin</topic><topic>Receptors</topic><topic>Sickle cell anemia</topic><topic>Sickle cell disease</topic><topic>Valine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kadhim, Doaa Amer</creatorcontrib><creatorcontrib>Al-Dujaili, Arshad Noori</creatorcontrib><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kadhim, Doaa Amer</au><au>Al-Dujaili, Arshad Noori</au><au>Ali, Tammar Hussein</au><au>Kadhem, Safaa Kareem</au><au>Al-Mussawi, Hana Kadum</au><au>Almurshedi, Ahmed Fadhil</au><au>Majeed, Sadiq</au><au>Hussain, Firas Faeq K.</au><au>Jawad, Laith Abdul Hassan M.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Assessment of soluble receptor for advance glycation end product level in patients suffering from sickle cell anemia related with nephropathy</atitle><btitle>AIP conference proceedings</btitle><date>2022-10-25</date><risdate>2022</risdate><volume>2398</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>Inherited hemolytic anemia represented by sickle cell disesae characterized by subsituition of valine for glutamic and causing adjusment of hemoglobin (Hb) quality also it was realized that Hb molecule subsituation of the β-globin chain at six circumstance caused to transfer of normal adult hemoglobin (HbA), to sickle hemoglobin (HbS). Current study was design to evaluate avery important markers for prediction or as prognostic to sickle cell anemia disease represented by Receptor for Advance of Glycation End Product (RAGE). Methods: The study was carried out in Al–Najaf province in Al-Zahraa TeachingHospital espically by cross-sectional study investigation at duration time from first July to tirty of November, 2019. This investigation was included fifty-five (suffering from sickle cell disease at age from 3-49 years, also appearantly healthy group as number was thirty. Evaluation of all critria were done by using Elisa technique for (RAGE) level and creatinine concentration and made a relatiom between both RAGE and creatinine with some of critria such as gender, body mass index, duration of disease and age .Results: Decrement was indicated significantly (P-Value<0.05) in Creatinine concentration, also increment (P-Value<0.05) Receptor for Advance of Glycation End Product (RAGE) level of in sickle cell anemia patients than control group. Serum Receptor for Advance of Glycation End Product (RAGE) indicated more significant levels for sickle cell anemia patients than healthy controls. Conclusion: The current study consider as aprediction of patients suffering from sickle cell disease and relation of RAGE with early renal disorder also with some complication.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/5.0093623</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2022, Vol.2398 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
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| source | AIP Journals Complete |
| subjects | Anemia Body size Creatinine Evaluation Hemoglobin Receptors Sickle cell anemia Sickle cell disease Valine |
| title | Assessment of soluble receptor for advance glycation end product level in patients suffering from sickle cell anemia related with nephropathy |
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