Abdominal aortic calcification, cardiac troponin I and atherosclerotic vascular disease mortality in older women

ObjectiveExamine if two inexpensive measures of atherosclerotic vascular diseases (ASVD), abdominal aortic calcification (AAC) and high-sensitivity cardiac troponin I (hs-cTnI) provide complementary information for 10-year ASVD mortality and all-cause mortality risk in older women.Methods908 communi...

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Veröffentlicht in:Heart (British Cardiac Society) 2022-08, Vol.108 (16), p.1274-1280
Hauptverfasser: Teh, Ryan, Prince, Richard L, Sim, Marc, Schousboe, John T, Raymond, Warren D, Szulc, Pawel, Lim, Wai, Hodgson, Jonathan M, Zhu, Kun, Kiel, Douglas P, Schultz, Carl, Thompson, Peter L, Lewis, Joshua R
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Sprache:eng
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Zusammenfassung:ObjectiveExamine if two inexpensive measures of atherosclerotic vascular diseases (ASVD), abdominal aortic calcification (AAC) and high-sensitivity cardiac troponin I (hs-cTnI) provide complementary information for 10-year ASVD mortality and all-cause mortality risk in older women.Methods908 community-dwelling women without prevalent ASVD (≥75 years) were followed-up between 2003 and 2013. AAC and plasma hs-cTnI measures were obtained in 2003. AAC was assessed on lateral spine images using a semiquantitative method (AAC24). Linked health records were used for mortality outcomes.ResultsMean±SD age was 79.9±2.6 years. 276 (30.4%) women died during follow-up, including 138 (15.2%) ASVD-related deaths. AAC24 and hs-cTnI were independently associated with ASVD and all-cause mortality (p
ISSN:1355-6037
1468-201X
DOI:10.1136/heartjnl-2021-319879