Rearranged Dichapetalin‐Type Triterpenoids with Cytotoxic Activity from Dichapetalum gelonioides

Comprehensive Summary Dichagelinoids A—C (1—3), three unusual dichapetalin‐type triterpenoids, together with two biogenetically related derivatives dichagelinoids D and E (4 and 5) were isolated and characterized by solid data from Dichapetalum gelonioides. Compounds 1—3 possess a common rearranged C ring and different C6—C2 modified motifs at the A rings. Biological evaluation revealed that compounds 1—3 showed distinct cytotoxic activity against the tested human cancer cell lines. Five dichapetalin‐type triterpenoids, dichagelinoids A—E (1—5), were isolated and characterized from Dichapetalum gelonioides. Compounds 1—3 featuring a common rearranged C ring and different C6—C2 modified motifs at the A rings, were verified as potent cytotoxic agents.