Secondary Metabolites of the Lichen Parmotrema cristiferum
A new C 41 -spiroterpenoid, norreticulatin ( 1 ), has been isolated from the thalli of Parmotrema cristiferum together with four known compounds, anadensin ( 2 ), fusicoauritone ( 3 ), ergosterol ( 4 ), and betulin ( 5 ). The structure of the new compound 1 was determined through spectroscopic and M...
Gespeichert in:
| Veröffentlicht in: | Chemistry of natural compounds 2022-09, Vol.58 (5), p.862-865 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | A new C
41
-spiroterpenoid, norreticulatin (
1
), has been isolated from the thalli of
Parmotrema cristiferum
together with four known compounds, anadensin (
2
), fusicoauritone (
3
), ergosterol (
4
), and betulin (
5
). The structure of the new compound
1
was determined through spectroscopic and MS analyses. Compound
1
exhibited potent inhibition, with an IC
50
value of 8.8 μM, much lower than that of the acarbose-positive control (IC
50
331 μM). |
|---|---|
| ISSN: | 0009-3130 1573-8388 |
| DOI: | 10.1007/s10600-022-03817-4 |