Synthesis of triazole-linked pseudo-oligosialic acid derivatives

Synthesis of triazole-linked pseudo-oligosialic acid derivatives

Using the Cu I -catalyzed 1,3-dipolar cycloaddition of terminal alkynes to azides, neuraminic acid di-, tri-, and tetrapseudosaccharides were synthesized, in which monosaccharide residues are linked by triazole intersaccharidic bridges.

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Veröffentlicht in:Russian chemical bulletin 2022-08, Vol.71 (8), p.1784-1793
Hauptverfasser: Savelyeva, N. Yu, Shpirt, A. M., Orlova, A. V., Chizhov, A. O., Kononov, L. O.
Format: Artikel
Sprache:eng
Schlagworte:
Alkynes
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Cycloaddition
Full Articles
Inorganic Chemistry
Monosaccharides
Organic Chemistry
Triazoles
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Beschreibung
Zusammenfassung:Using the Cu I -catalyzed 1,3-dipolar cycloaddition of terminal alkynes to azides, neuraminic acid di-, tri-, and tetrapseudosaccharides were synthesized, in which monosaccharide residues are linked by triazole intersaccharidic bridges.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-022-3590-3