Halogen-Containing 4-Hydroxybenzylidene-Rhodanines as Fast Protein Fluorogens
— We report a series of ( Z )-5-(4-hydroxybenzylidene)-2-thioxothiazolidin-4-ones containing halogens at different positions of the benzylidene moiety. The new compounds exhibit fluorogenic properties and form fluorescent complexes with FAST. We showed that 3-halogen-4-hydroxybenzyliden-rhodanines c...
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| Veröffentlicht in: | Russian journal of bioorganic chemistry 2022-10, Vol.48 (5), p.1105-1108 |
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| container_end_page | 1108 |
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| container_issue | 5 |
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| container_title | Russian journal of bioorganic chemistry |
| container_volume | 48 |
| creator | Sokolov, A. I. Baleeva, N. S. Baranov, M. S. |
| description | —
We report a series of (
Z
)-5-(4-hydroxybenzylidene)-2-thioxothiazolidin-4-ones containing halogens at different positions of the benzylidene moiety. The new compounds exhibit fluorogenic properties and form fluorescent complexes with FAST. We showed that 3-halogen-4-hydroxybenzyliden-rhodanines can be used as ligands for the fluorogen-activating protein FAST in fluorescence microscopy. |
| doi_str_mv | 10.1134/S1068162022050247 |
| format | Article |
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We report a series of (
Z
)-5-(4-hydroxybenzylidene)-2-thioxothiazolidin-4-ones containing halogens at different positions of the benzylidene moiety. The new compounds exhibit fluorogenic properties and form fluorescent complexes with FAST. We showed that 3-halogen-4-hydroxybenzyliden-rhodanines can be used as ligands for the fluorogen-activating protein FAST in fluorescence microscopy.</description><identifier>ISSN: 1068-1620</identifier><identifier>EISSN: 1608-330X</identifier><identifier>DOI: 10.1134/S1068162022050247</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Biochemistry ; Biomedical and Life Sciences ; Biomedicine ; Bioorganic Chemistry ; Fluorescence ; Halogens ; Letters to the Editor ; Life Sciences ; Organic Chemistry ; Proteins</subject><ispartof>Russian journal of bioorganic chemistry, 2022-10, Vol.48 (5), p.1105-1108</ispartof><rights>Pleiades Publishing, Ltd. 2022. ISSN 1068-1620, Russian Journal of Bioorganic Chemistry, 2022, Vol. 48, No. 5, pp. 1105–1108. © Pleiades Publishing, Ltd., 2022. Russian Text © The Author(s), 2022, published in Bioorganicheskaya Khimiya, 2022, Vol. 48, No. 5, pp. 616–620.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c198t-6acbee3f3eadb7b9e219ce91564d5c4763f601a5f9c0639b3ed4b5012f82e8a13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S1068162022050247$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S1068162022050247$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Sokolov, A. I.</creatorcontrib><creatorcontrib>Baleeva, N. S.</creatorcontrib><creatorcontrib>Baranov, M. S.</creatorcontrib><title>Halogen-Containing 4-Hydroxybenzylidene-Rhodanines as Fast Protein Fluorogens</title><title>Russian journal of bioorganic chemistry</title><addtitle>Russ J Bioorg Chem</addtitle><description>—
We report a series of (
Z
)-5-(4-hydroxybenzylidene)-2-thioxothiazolidin-4-ones containing halogens at different positions of the benzylidene moiety. The new compounds exhibit fluorogenic properties and form fluorescent complexes with FAST. We showed that 3-halogen-4-hydroxybenzyliden-rhodanines can be used as ligands for the fluorogen-activating protein FAST in fluorescence microscopy.</description><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bioorganic Chemistry</subject><subject>Fluorescence</subject><subject>Halogens</subject><subject>Letters to the Editor</subject><subject>Life Sciences</subject><subject>Organic Chemistry</subject><subject>Proteins</subject><issn>1068-1620</issn><issn>1608-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1UEtLxDAQDqLguvoDvBU8R2eSJm2PsriusKL4AG8lbadrl5po0gXrrzfLCh7Ey8zA92I-xk4RzhFlevGIoHPUAoQABSLN9tgENeRcSnjZj3eE-RY_ZEchrAEQQOUTdrswvVuR5TNnB9PZzq6SlC_GxrvPsSL7NfZdQ5b4w6trTIQpJCYkcxOG5N67gTqbzPuN81uTcMwOWtMHOvnZU_Y8v3qaLfjy7vpmdrnkNRb5wLWpKyLZSjJNlVUFCSxqKlDptFF1mmnZakCj2qIGLYtKUpNWClC0uaDcoJyys53vu3cfGwpDuXYbb2NkKTLM4s8qzinDHav2LgRPbfnuuzfjxxKh3LZW_mktasROEyLXrsj_Ov8v-gbidW6y</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Sokolov, A. I.</creator><creator>Baleeva, N. S.</creator><creator>Baranov, M. S.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20221001</creationdate><title>Halogen-Containing 4-Hydroxybenzylidene-Rhodanines as Fast Protein Fluorogens</title><author>Sokolov, A. I. ; Baleeva, N. S. ; Baranov, M. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c198t-6acbee3f3eadb7b9e219ce91564d5c4763f601a5f9c0639b3ed4b5012f82e8a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Bioorganic Chemistry</topic><topic>Fluorescence</topic><topic>Halogens</topic><topic>Letters to the Editor</topic><topic>Life Sciences</topic><topic>Organic Chemistry</topic><topic>Proteins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sokolov, A. I.</creatorcontrib><creatorcontrib>Baleeva, N. S.</creatorcontrib><creatorcontrib>Baranov, M. S.</creatorcontrib><collection>CrossRef</collection><jtitle>Russian journal of bioorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sokolov, A. I.</au><au>Baleeva, N. S.</au><au>Baranov, M. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Halogen-Containing 4-Hydroxybenzylidene-Rhodanines as Fast Protein Fluorogens</atitle><jtitle>Russian journal of bioorganic chemistry</jtitle><stitle>Russ J Bioorg Chem</stitle><date>2022-10-01</date><risdate>2022</risdate><volume>48</volume><issue>5</issue><spage>1105</spage><epage>1108</epage><pages>1105-1108</pages><issn>1068-1620</issn><eissn>1608-330X</eissn><abstract>—
We report a series of (
Z
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| identifier | ISSN: 1068-1620 |
| ispartof | Russian journal of bioorganic chemistry, 2022-10, Vol.48 (5), p.1105-1108 |
| issn | 1068-1620 1608-330X |
| language | eng |
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| subjects | Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Fluorescence Halogens Letters to the Editor Life Sciences Organic Chemistry Proteins |
| title | Halogen-Containing 4-Hydroxybenzylidene-Rhodanines as Fast Protein Fluorogens |
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