Opportunities and challenges in studying the extracellular vesicle corona

The extracellular vesicle (EV) surface corona is emerging as a crucial mediator of EV functions. This Comment discusses the roles and biogenesis of the EV corona, as well as the importance of controls to determine whether a biological effect is attributable to the internal EV cargo or to the corona...

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Veröffentlicht in:Nature cell biology 2022-09, Vol.24 (9), p.1322-1325
1. Verfasser: Buzas, Edit I.
Format: Artikel
Sprache:eng
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Zusammenfassung:The extracellular vesicle (EV) surface corona is emerging as a crucial mediator of EV functions. This Comment discusses the roles and biogenesis of the EV corona, as well as the importance of controls to determine whether a biological effect is attributable to the internal EV cargo or to the corona associated with the EV exofacial surface.
ISSN:1465-7392
1476-4679
DOI:10.1038/s41556-022-00983-z