P106 Potentially missed cancer at endoscopy in Barrett’s oesophagus: a national study of rate and associated factors

Background and AimPotentially missed or post endoscopy upper gastrointestinal cancer (PEUGIC) is UGI cancer (UGIC) diagnosed within 6 to 36 months of an endoscopy without a cancer diagnosis. We examined the PEUGIC rate among patients with Barrett’s oesophagus in England and associated factors.MethodsUsing linked National Cancer Registration and Analysis Service and Hospital Episode Statistics databases, all patients diagnosed with UGIC between 2012-2018 who had undergone an endoscopy within 3 years prior to UGIC diagnosis, and a previous ICD10 coding for Barrett’s oesophagus (K22.7) were identified. Multivariable logistic regression analysis explored factors associated with PEUGIC in Barrett’s oesophagus. Funnel plot with superimposed control limits representing two and three standard deviations from the mean was produced to assess variations in Barrett’s PEUGIC rates between trusts.Results12,231 UGIC in patients with Barrett’s oesophagus studied. UGIC in patients with Barrett’s were diagnosed at an earlier stage (I&II) compared to UGIC patients without Barrett’s (40% vs 20% p