Pancreatic Hormones, the Composition of Saturated Fatty Acids, and Their Relationship with Glucose Levels, Depending on the Body Mass Index in Residents of the Arctic
The content of pancreatic hormones, the composition of saturated fatty acids (SFAs), and their relationship with glucose (Glu) levels depending on the body mass index (BMI) were studied in the aboriginal (A) and local Caucasian (LC) populations of the Arctic. Differences in the range of SFAs in the...
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Veröffentlicht in: | Biology bulletin of the Russian Academy of Sciences 2022-08, Vol.49 (4), p.333-347 |
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description | The content of pancreatic hormones, the composition of saturated fatty acids (SFAs), and their relationship with glucose (Glu) levels depending on the body mass index (BMI) were studied in the aboriginal (A) and local Caucasian (LC) populations of the Arctic. Differences in the range of SFAs in the LC population with a BMI of 18.4 < BMI < 25 kg/m
2
were revealed, which are manifested in a significant high content of medium-and long-chain SFAs, Caro, and proinsulin/insulin values, and a low level of short-chain SFAs, insulin (Ins), and HOMA values (
p
< 0.001), which indicates higher hyperglycemic states compared to A. No significant changes were found in the content of the C-peptide in A, and in LC its content significantly increased with an increase in BMI. The study of these indicators in individuals with a BMI > 25 kg/m
2
of different ethnic backgrounds showed a similar picture, but with a greater degree of severity. |
doi_str_mv | 10.1134/S1062359022030049 |
format | Article |
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2
were revealed, which are manifested in a significant high content of medium-and long-chain SFAs, Caro, and proinsulin/insulin values, and a low level of short-chain SFAs, insulin (Ins), and HOMA values (
p
< 0.001), which indicates higher hyperglycemic states compared to A. No significant changes were found in the content of the C-peptide in A, and in LC its content significantly increased with an increase in BMI. The study of these indicators in individuals with a BMI > 25 kg/m
2
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2
were revealed, which are manifested in a significant high content of medium-and long-chain SFAs, Caro, and proinsulin/insulin values, and a low level of short-chain SFAs, insulin (Ins), and HOMA values (
p
< 0.001), which indicates higher hyperglycemic states compared to A. No significant changes were found in the content of the C-peptide in A, and in LC its content significantly increased with an increase in BMI. The study of these indicators in individuals with a BMI > 25 kg/m
2
of different ethnic backgrounds showed a similar picture, but with a greater degree of severity.</description><subject>Animal and Human Physiology</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Body mass index</subject><subject>Cell Biology</subject><subject>Ecology</subject><subject>Fatty acids</subject><subject>Insulin</subject><subject>Life Sciences</subject><subject>Pancreas</subject><subject>Zoology</subject><issn>1062-3590</issn><issn>1608-3059</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kU9LAzEQxRdRsFY_gLeAV1cz2XT_HGu1VagoVs9LmszalDZZk1TtF_JzmqWCB_E0A_N77w28JDkFegGQ8csZ0Jxlg4oyRjNKebWX9CCnZZrRQbUf93hOu_thcuT9kkYk46yXfD0KIx2KoCW5tW5tDfpzEhZIRnbdWq-DtobYhsxE2DgRUJGxCGFLhlKrSAqjyPMCtSNPuBId7Be6JR86LMhktZHWI5niO64ie40tGqXNK4mWXcSVVVtyL7wnd0bhJ9Emunit0ATfZXbM0Mn423Fy0IiVx5Of2U9exjfPo9t0-jC5Gw2nqYSqDClneQmS4xxKXiCfN6XEUhUSAYBVohKiklAM8kzlPKdSsYbKis95jhSLQs2zfnK2822dfdugD_XSbpyJkTUrAChlwLNIwY6SznrvsKlbp9fCbWugdVdH_aeOqGE7jY-seUX36_y_6Bv-AY1D</recordid><startdate>20220801</startdate><enddate>20220801</enddate><creator>Bichkaeva, F. A.</creator><creator>Gretskaya, T. B.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20220801</creationdate><title>Pancreatic Hormones, the Composition of Saturated Fatty Acids, and Their Relationship with Glucose Levels, Depending on the Body Mass Index in Residents of the Arctic</title><author>Bichkaeva, F. A. ; Gretskaya, T. B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c198t-42681c4eb1847e4bf8ce8d7ce11129a9aa9c17563d6460cd2f0c94b46e0e77db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animal and Human Physiology</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Body mass index</topic><topic>Cell Biology</topic><topic>Ecology</topic><topic>Fatty acids</topic><topic>Insulin</topic><topic>Life Sciences</topic><topic>Pancreas</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bichkaeva, F. A.</creatorcontrib><creatorcontrib>Gretskaya, T. B.</creatorcontrib><collection>CrossRef</collection><jtitle>Biology bulletin of the Russian Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bichkaeva, F. A.</au><au>Gretskaya, T. B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pancreatic Hormones, the Composition of Saturated Fatty Acids, and Their Relationship with Glucose Levels, Depending on the Body Mass Index in Residents of the Arctic</atitle><jtitle>Biology bulletin of the Russian Academy of Sciences</jtitle><stitle>Biol Bull Russ Acad Sci</stitle><date>2022-08-01</date><risdate>2022</risdate><volume>49</volume><issue>4</issue><spage>333</spage><epage>347</epage><pages>333-347</pages><issn>1062-3590</issn><eissn>1608-3059</eissn><abstract>The content of pancreatic hormones, the composition of saturated fatty acids (SFAs), and their relationship with glucose (Glu) levels depending on the body mass index (BMI) were studied in the aboriginal (A) and local Caucasian (LC) populations of the Arctic. Differences in the range of SFAs in the LC population with a BMI of 18.4 < BMI < 25 kg/m
2
were revealed, which are manifested in a significant high content of medium-and long-chain SFAs, Caro, and proinsulin/insulin values, and a low level of short-chain SFAs, insulin (Ins), and HOMA values (
p
< 0.001), which indicates higher hyperglycemic states compared to A. No significant changes were found in the content of the C-peptide in A, and in LC its content significantly increased with an increase in BMI. The study of these indicators in individuals with a BMI > 25 kg/m
2
of different ethnic backgrounds showed a similar picture, but with a greater degree of severity.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1062359022030049</doi><tpages>15</tpages></addata></record> |
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subjects | Animal and Human Physiology Biochemistry Biomedical and Life Sciences Body mass index Cell Biology Ecology Fatty acids Insulin Life Sciences Pancreas Zoology |
title | Pancreatic Hormones, the Composition of Saturated Fatty Acids, and Their Relationship with Glucose Levels, Depending on the Body Mass Index in Residents of the Arctic |
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