A Procedure for Preparing Effective Immunomodulators and Antioxidants: 5-Hydroxy-6-methyluracil and 5-Hydroxy-1,3,6-trimethyluracil

5-Hydroxy-6-methyluracil is an acting agent of Oxymethyluracilum drug, an immunostimulator with a broad spectrum of pharmacological activity. Its synthesis is based on the 6-methyluracil oxidation with (NH 4 ) 2 S 2 O 8 under the conditions of Elbs reaction. The Elbs oxidation of 6-methyluracil in the presence of metal phthalocyanine oxidation catalysts was studied. Conditions allowing the 5-hydroxy-6-methyluracil yield to be increased to 95% were found. The most active catalysts are Fe(II), Fe(III), and Co phthalocyanines.