Transformation from lung adenocarcinoma to combined small cell carcinoma in pleural effusion after treatment with osimertinib

The transformation of lung adenocarcinoma to combined small cell lung cancer is a rare mechanism of acquired resistance to EGFR tyrosine kinase inhibitors. This case describes this mechanism in a pleural effusion of a young patient treated with osimertinib for 18 months.

Bibliographische Detailangaben

Veröffentlicht in:	CYTOPATHOLOGY 2022-09, Vol.33 (5), p.633-635
Hauptverfasser:	Frankel, Diane, Kaspi, Elise, Liprandi, Agnès, Dales, Jean‐Philippe, Roll, Patrice
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma combined small cell lung cancer Genetics Life Sciences lung adenocarcinoma osimertinib Pleural effusion Protein-tyrosine kinase Small cell lung carcinoma transformation
Online-Zugang:	Volltext
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