Multilayer nanostructured system for oral insulin delivery

A method to obtain a multilayer insulin-containing composition in a nanostructured form consisting of layers: gold-chitosan-insulin-chitosan nanoparticles was developed. The size of the fully formed multicomponent system was 178 nm.The outer layer of chitosan protects insulin from the damaging effec...

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Veröffentlicht in:	Journal of polymer research 2022-09, Vol.29 (9), Article 378
Hauptverfasser:	Apryatina, Kristina V., Glazova, Irina A., Koryagin, Alexander S., Zaitsev, Sergey D., Smirnova, Larisa A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal experimentation Blood Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chitosan Composition Diabetes therapy Dosage Effectiveness Gastrointestinal system Glycosylated hemoglobin Hemoglobin Industrial Chemistry/Chemical Engineering Insulin Multilayers Nanoparticles Nanostructure Original Paper Polymer Sciences Proteases Type 1 diabetes
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