Systematic Screening and Therapeutic Evaluation of Glyconanoparticles with Differential Cancer Affinities for Targeted Cancer Therapy (Adv. Mater. 30/2022)

Cancer Therapy As glycocalyx‐directed binding interactions are prevalent in cancer cells and are used for cell–cell communication and cell adhesion through carbohydrate‐mediated interactions, Hee‐Seung Lee, Sangyong Jon, and co‐workers have developed a nanomedicine platform based on a library of glycocalyx‐mimicking nanoparticles that enables screening and identification of cancer‐cell‐selective glyconanoparticles, as described in article number 2203993. This work demonstrates the potential of the glycocalyx‐mimicking nanoparticle platform for use in targeted cancer therapy.