Reversal of Oral Vitamin K Antagonists Using Prothrombin Complex Concentration Prior to IV tPA Administration

Herein, we report two acute ischemic stroke cases that we used prothrombin complex to reverse the effects of warfarin in order to apply intravenous thrombolytic treatment. To the best of our knowledge, there are only limited amount of cases that prothrombin complex concentrates were applied prior to...

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Veröffentlicht in:Neurology India 2022-05, Vol.70 (3), p.1238-1239
Hauptverfasser: Salt, Irmak, Aslan, Işıl, Özgenç Biçer, Çisil, Gözke, Eren
Format: Artikel
Sprache:eng
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Zusammenfassung:Herein, we report two acute ischemic stroke cases that we used prothrombin complex to reverse the effects of warfarin in order to apply intravenous thrombolytic treatment. To the best of our knowledge, there are only limited amount of cases that prothrombin complex concentrates were applied prior to intravenous thrombolytic treatment administration. As one of the biggest acute stroke clinics in our country, we aim to open a discussion for this treatment to be fully researched and understood.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.349620