SPASER as Nanoprobe for Biological Applications: Current State and Opportunities

Since the concept of surface plasmon amplification by stimulated emission of radiation (SPASER) was proposed in 2003, great progresses have been made on two kinds of plasmonic nanolasers, namely SPASER device and SPASER nanoparticle. In comparison, SPASER nanoparticle, with ultra‐narrow emission lin...

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Veröffentlicht in:Laser & photonics reviews 2022-07, Vol.16 (7), p.n/a
Hauptverfasser: Wang, Jian‐Hua, Wang, Shao‐Peng, Melentiev, Pavel N., Balykin, Victor I., Xu, Jing‐Juan, Chen, Hong‐Yuan, Kang, Bin
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Sprache:eng
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Zusammenfassung:Since the concept of surface plasmon amplification by stimulated emission of radiation (SPASER) was proposed in 2003, great progresses have been made on two kinds of plasmonic nanolasers, namely SPASER device and SPASER nanoparticle. In comparison, SPASER nanoparticle, with ultra‐narrow emission line, small size, and good biocompatibility, is a kind of promising luminescent nanoprobe and has a bright application prospect in biomedical imaging and sensing. Hence, it is gradually becoming an attractive research hotspot in the world. However, as the research on SPASER nanoparticle is still in its infancy, there are still lots of problems to be solved before it is widely applied. In this paper, the latest research advances of SPASER nanoparticles and their biological applications are reviewed. Besides existing problems, challenges and opportunities of SPASER nanoparticles as next generation luminescent nanoprobes are discussed as well. Researches show that the threshold conditions and emission wavelength of SPASER (surface plasmon amplification by stimulated emission of radiation) nanoparticles can be altered by adjusting the plasmonic cavity and gain material. “SPASER probes family” is expected to be developed and combined with commercial biological instruments, to open up a new path for future fluorescence‐based multichannel bioanalysis (sensing, imaging, and cytometry).
ISSN:1863-8880
1863-8899
DOI:10.1002/lpor.202100622