Two New Antibacterial Anthraquinones from the Twigs of Cassia alata

Two New Antibacterial Anthraquinones from the Twigs of Cassia alata

Two new anthraquinones, 2,6-dimethyl-3-hydroxy-5-methoxyanthraquinone ( 1 ) and 2,5-dimethyl-6-hydroxy-3-methoxyanthraquinone ( 2 ), were isolated from the twigs of Cassia alata . Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 an...

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Veröffentlicht in:Chemistry of natural compounds 2022-05, Vol.58 (3), p.414-417
Hauptverfasser: Yang, Wen-Wu, Xiao, Dong, Yin, Geng-Yun, Deng, Le-Le, Zhang, Jian-Duo, Jiang, Jia-Rui, Xu, Li, Zhu, Ling-Cao, Zhou, Min, Hu, Qiu-Fen, Mi, Qi-Li, Shi, Jian-Quan
Format: Artikel
Sprache:eng
Schlagworte:
Anthraquinones
Antibacterial agents
Beans
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Legumes
Microorganisms
Mimosaceae
NMR
Nuclear magnetic resonance
Organic Chemistry
Plant Sciences
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Zusammenfassung:Two new anthraquinones, 2,6-dimethyl-3-hydroxy-5-methoxyanthraquinone ( 1 ) and 2,5-dimethyl-6-hydroxy-3-methoxyanthraquinone ( 2 ), were isolated from the twigs of Cassia alata . Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their antibacterial activity. The results showed that both compounds exhibited high antibacterial activity against 11 microbial strains isolated from the saliva of smokers.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03696-9