Periodic Limb Movements during Sleep and the Clinical-Morphological Signs of Cerebral Microangiopathy

Periodic Limb Movements during Sleep and the Clinical-Morphological Signs of Cerebral Microangiopathy

Objectives. To establish the relationship between the extent of white matter lesions and the degree of reductions in cognitive functions with periodic limb movements (PLM) in patients with cerebral microangiopathy (CMA). Materials and methods. A total of 34 patients with established diagnoses of CMA...

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Veröffentlicht in:Neuroscience and behavioral physiology 2022-03, Vol.52 (3), p.326-329
Hauptverfasser: Spektor, E. D., Poluektov, M. G.
Format: Artikel
Sprache:eng
Schlagworte:
Behavioral Sciences
Biomedical and Life Sciences
Biomedicine
Cognitive ability
Magnetic resonance imaging
Measuring techniques
Neurobiology
Neuroimaging
Neuropsychology
Neurosciences
Patients
Psychology
Sleep
Substantia alba
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Zusammenfassung:Objectives. To establish the relationship between the extent of white matter lesions and the degree of reductions in cognitive functions with periodic limb movements (PLM) in patients with cerebral microangiopathy (CMA). Materials and methods. A total of 34 patients with established diagnoses of CMA (12 men, 22 women, mean age 66.9 years) were studied. The investigation protocol included nocturnal actigraphy and cardiorespiratory monitoring of nocturnal sleep, neuropsychological testing, and assessment of neuroimaging markers of CMA using brain MRI scan data. Depending on the PLM index, study (PLM index ≥15 episodes/h) and control (PLM index
ISSN:0097-0549
1573-899X
DOI:10.1007/s11055-022-01243-1